Problem:
Rhino 5 displays this error and will not run:

Cause:
Unknown.

Solution:

1. Uninstall the four Rhino 5 program components using Windows Control Panel:
   1. Rhinoceros 5
   2. Rhinoceros 5 (64-bit)
   3. Rhinoceros 5 Help Media
   4. Rhinoceros 5 Language Pack Installer
2. Run Windows Check for Updates to make sure all Windows Updates have been installed
3. Download and install the latest full version of Rhino 5 from http://www.rhino3d.com/download/rhino/5/latest

Note:
Another user reported having the same error even after reinstalling Rhino, but running a “Repair” on the 64-bit Rhino in Programs and Features corrected the error for her.

References:
SupportBee tickets: 9679912, 9525401, 9518774, 15173831, 15377325